Abstract:
: Plants of the Suregada Roxb. ex Rottler (formerly Gelonium Roxb. ex Willd) are utilized to
treat various ailments, namely, hepatic, gum diseases, pyrexia, eczema, and venereal diseases. This
review links the reported compounds to ethnomedicinal uses through pharmacological activities.
The compounds possess anticancer, anti-allergic, antibacterial, anti-inflammatory, antioxidant, and
anti-HIV properties. From the previous reports, 32 known species of the Suregada genus have been
investigated morphologically, and nine were investigated for their phytochemistry and pharmacology.
Phytochemistry, ethnomedicinal, and pharmacological uses of the other 23 Suregada species are not
known and/or not reported. In this review, abietane diterpenoids are the main compounds expressed
by the Suregada, accounting for 71 of the 114 reported compounds. Ten triterpenoids and sterols, one
aliphatic, two lignans, five flavonoids, and twenty-one nitrogen-containing compounds have been
reported from the genus.
